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gene 850 words KG: HCN3
Contents

HCN3

🧬 Gene Info
Gene SymbolHCN3
Chromosome1p22.2
Protein TypeGene
Functionencodes a voltage-gated ion channel subunit that contributes to hyperpolarization-activated inward current (Ih).
GeneCardsHCN3
Human Protein AtlasHCN3
Associated Diseasesneurodegeneration
KG Connections10 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

HCN1-Mediated Resonance Frequency Stabilization Therapy
Score: 0.65APOE-Dependent Autophagy Restoration
Score: 0.89

Related Analyses (2)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Related Experiments (5)

s:** - Test whether HCN1 knockout specifically in EC layer I
falsification · proposed · Score: 0.40cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40Non-Motor Symptom Progression in Parkinson's Disease — Mecha
clinical · proposed · Score: 0.40Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (6)

GABA (Gamma-Aminobutyric Acid) - Neurodegenerative Dise
biomarker · KG edge: expressed_inDopamine Transporter Modulators for Parkinson's Disease
company · KG edge: expressed_inNeuRon Therapeutics
company · KG edge: expressed_inNeurodegeneration
disease · KG edge: implicated_inNeurons
entity · KG edge: expressed_in

Knowledge Graph (10 edges)

HCN1 expressed_in HCN3
HCN3 expressed_in Ventral Tegmental Area
HCN3 expressed_in HCN1
HCN1 co_mentioned HCN3
HCN3 expressed_in GABA
HCN3 expressed_in Neuron
HCN3 expressed_in NEURONS
HCN3 expressed_in DOPAMINE
GABA co_mentioned HCN3
EPILEPSY associated_with HCN3

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