| Gene Symbol | MARCHF1 |
| Aliases | Membrane-Associated RING-CH Finger 1 |
| Protein Type | Ligase |
| Function | is a membrane-associated E3 ubiquitin ligase belonging to the MARCH family of RING-CH (Really Interesting New Gene-CH) domain-containing proteins. |
| Primary Expression | immune cells but has emerging roles in neuroinflammation and neurodegeneration |
| Pathways | Notch |
| GeneCards | MARCHF1 |
| Human Protein Atlas | MARCHF1 |
| CD4 | Monoubiquitination |
| CD8α | Monoubiquitination |
| MHC class II | Polyubiquitination |
| B7-2 (CD86) | Ubiquitination |
| Fas | Ubiquitination |
| Notch | Ubiquitination |
| Protein | Alternative Name |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |