gene 3,211 words KG: MYO6 2026-03-27
kind:genesection:genesstate:published
Contents

MYO6 — Myosin VI

🧬 Gene Info
Gene SymbolMYO6
Full NameMyosin VI
Chromosome6q13
Function### Cellular Functions
Primary ExpressionInner ear, kidney, brain, testis
Molecular Weight~170 kDa (heavy chain)
UniProt ID[Q9UMR5](https://www.uniprot.org/uniprot/Q9UMR5)
Ensembl IDENSG00000128595
OMIM600970
GeneCardsMYO6
Human Protein AtlasMYO6
Motor ClassUnconventional myosin (class VI)
DirectionalityMinus-end directed (unique among myosins)
Motor DomainN-terminal motor domain with ATPase activity
Tail DomainC-terminal cargo-binding domain (dimerization)
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (19)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
LRP1-Dependent Tau Uptake Disruption
Score: 0.44
APOE-Dependent Autophagy Restoration
Score: 0.61

Related Analyses (6)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Senescent Cell Clearance in Neurodegeneration
mechanism · Pages share 4 hypotheses
RNA-Targeted Therapies in Neurodegeneration
mechanism · Pages share 4 hypotheses
PPAR Signaling Pathway in Neurodegeneration
mechanism · Pages share 4 hypotheses
Neurovascular Unit Dysfunction in Neurodegeneration
mechanism · Pages share 4 hypotheses