gene 1,314 words KG: NDUFB1 2026-03-27
kind:genesection:genesstate:published
Contents

NDUFB1 — NADH:ubiquinone Oxidoreductase Subunit B1

🧬 Gene Info
Gene SymbolNDUFB1
Full NameNADH:ubiquinone Oxidoreductase Subunit B1 (Complex I-B8)
AliasesNADH:ubiquinone Oxidoreductase Subunit B1
Chromosome2q33.3
Functionencodes a crucial accessory subunit of mitochondrial Complex I (NADH:ubiquinone oxidoreductase), the largest complex of the mitochondrial electron transport chain[@fearnley1992].
Primary ExpressionUbiquitous (highest in brain, heart, skeletal muscle)
Molecular Weight11 kDa
Amino Acids104 aa
Pathwaysoxidative phosphorylation
UniProt IDO75489
NCBI Gene ID4706
Ensembl IDENSG00000170733
GeneCardsNDUFB1
Human Protein AtlasNDUFB1
Protein Length104 amino acids
InteractionsATP5MC1, COX17
KG Connections4 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (1)

SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.51

Related Analyses (2)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived

Related Experiments (14)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (4 edges)

NDUFB1 regulates oxidative phosphorylation
NDUFB1 participates_in mitochondrial function
ATP5MC1 activates NDUFB1
COX17 activates NDUFB1