| Gene Symbol | PPP1R15B |
| Full Name | Protein Phosphatase 1 Regulatory Subunit 15B |
| Aliases | Protein Phosphatase 1 Regulatory Subunit 15B (CReP) |
| Chromosome | 1q21.3 |
| Protein Type | Phosphatase |
| Function | This complex specifically targets the alpha subunit of eukaryotic initiation factor 2 (eIF2α) |
| Amino Acids | 684 aa |
| UniProt ID | Q9H0X4 |
| NCBI Gene ID | 84919 |
| Ensembl ID | ENSG00000167524 |
| GeneCards | PPP1R15B |
| Human Protein Atlas | PPP1R15B |
| CReP protein | 684 amino acids, contains PP1-binding motif |
| PP1 catalytic subunit | Provides the phosphatase activity |
| Substrate specificity | The CReP regulatory subunit directs PP1 to dephosphorylate specifically eIF2α |
| Associated Diseases | neurodegeneration |
| Interactions | MUL1, UBIQUITIN |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |