| Gene Symbol | UBIQUITIN |
| Function | is a highly conserved 76-amino acid protein that covalently attaches to target proteins to mark them for various cellular fates. |
| Pathways | Adaptive Immunity, Akt, Angiogenesis, Apoptosis, Autophagy |
| GeneCards | UBIQUITIN |
| Human Protein Atlas | UBIQUITIN |
| Linkage | Function |
| K48 | Proteasomal degradation |
| K63 | Endocytosis, signaling, autophagy |
| K11 | Cell cycle regulation |
| K27 | DNA damage response |
| K33 | Mitochondrial quality control |
| K29 | Lysosomal degradation |
| K6 | Mitochondrial dynamics |
| M1 (linear) | NF-κB signaling |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | proteolysis-targeting chimeras, RAPAMYCIN |
| Interactions | DDB1, ATG12, ATG16L1, ATG5, P62, KEAP1 |
| KG Connections | 4017 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |