gene 2,514 words KG: SIGLEC10 2026-03-24
kind:genesection:genesstate:published
Contents

SIGLEC10 — Sialic Acid Binding Ig-Like Lectin 10

🧬 Gene Info
Gene SymbolSIGLEC10
Full NameSialic Acid Binding Ig-Like Lectin 10
Chromosome19q13.4
Functionis a member of the Siglec family of cell surface lectins that recognize sialic acid residues on glycoconjugates.
Primary ExpressionB cells, monocytes, eosinophils, dendritic cells
Molecular Weight~60 kDa
Amino Acids553 aa
Exons12
UniProt IDQ9H7M1
NCBI Gene ID89792
GeneCardsSIGLEC10
Human Protein AtlasSIGLEC10
FeatureValue
Genomic Coordinateschr19:50,884,231-50,901,213 (GRCh38)
Exon Count12
Associated DiseasesGlioma
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (2)

Selective Acid Sphingomyelinase Modulation Therapy
Score: 0.65
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.44

Related Analyses (6)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (6 edges)

SIGLEC10 mediates Tumor Immune Escape
SIGLEC10 inhibits Macrophage Phagocytosis
SIGLEC10 associated_with Glioma
ITGA3 binds SIGLEC10
CD24 binds SIGLEC10
ITGB1 binds SIGLEC10