gene 2,710 words KG: SORCS2 2026-03-28
kind:genesection:genesstate:publishedtopic:alzheimertopic:parkinsontopic:sortilin-familytopic:neurotrophin-receptortopic:traffickingtopic:synaptic-function
Contents

SORCS2 Gene

🧬 Gene Info
Gene SymbolSORCS2
Full NameSortilin-Related VPS10 Domain Containing Receptor 2
AliasesSortilin-related VPS10 domain-containing receptor 2
Chromosome4p16.1
Protein TypeReceptor
Functionencodes a member of the sortilin family of VPS10P domain receptors.
Subcellular Localization- **Di-leucine motif (DDQSDL)** — Mediates endosomal sorting
Amino Acids835 aa
Exons24
PathwaysNeurogenesis
UniProt IDQ9Y6I9
NCBI Gene ID22999
Ensembl IDENSG00000145945
OMIM606284
GeneCardsSORCS2
Human Protein AtlasSORCS2
Associated Diseasesneurodegeneration
KG Connections47 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph