gene 1,092 words KG: SORCS1 2026-03-21
kind:genesection:genesstate:published
Contents

SORCS1 Gene

🧬 Gene Info
Gene SymbolSORCS1
Full NameSortilin-Related VPS10 Domain Containing Receptor 1
Chromosome10q25.3
Protein TypeReceptor
FunctionSORCS1 encodes a member of the sortilin family of VPS10P domain receptors.
Primary Expressionthe brain that participates in intracellular protein trafficking and signaling
Subcellular Localization**BACE1 interaction** - Affects β-secretase processing of APP
Molecular Weight116 kDa
Amino Acids600 aa
PathwaysNeurogenesis
UniProt IDQ9Y6J0
NCBI Gene ID22998
Ensembl IDENSG00000146433
OMIM606283
GeneCardsSORCS1
Human Protein AtlasSORCS1
Associated DiseasesAls, Alzheimer, Bipolar, Coronary Artery Disease, Diabetes
KG Connections54 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph