gene 1,015 words KG: ST6GALNAC5 2026-03-29
kind:genesection:genestopic:alzheimersstate:publishedst6galnac5sialyltransferaseastrocytespatial-memory
Contents

ST6GALNAC5 Gene

🧬 Gene Info
Gene SymbolST6GALNAC5
Full NameST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
Chromosome1p31.3
Protein TypeSialyltransferase
FunctionSialylation of glycoproteins, neural cell adhesion
Primary ExpressionAstrocytes, brain
UniProt IDQ9H0X9
NCBI Gene ID256297
Ensembl IDENSG00000160584
GeneCardsST6GALNAC5
Human Protein AtlasST6GALNAC5
ApproachRationale
ST6GALNAC5 knockdownImproves spatial memory in AD mice
Small molecule inhibitorsReduce enzyme activity
CRISPR gene therapyPrecise targeting
Associated DiseasesAlzheimer's disease
KG Connections5 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph