| Gene Symbol | U2AF2 |
| Chromosome | 19q13.42 |
| Function | is a core spliceosomal protein essential for the recognition of the 3' splice site during pre-mRNA splicing. |
| Molecular Weight | 65kDa |
| Amino Acids | 475 aa |
| Pathways | pathway: **Assembly Sequence:** |
| Ensembl ID | ENSG00000163251 |
| GeneCards | U2AF2 |
| Human Protein Atlas | U2AF2 |
| N-terminal RS domain | Arginine-serine repeats for protein-protein interactions |
| RNA recognition motif (RRM) domains | Multiple RRMs for RNA binding |
| Polypyrimidine tract binding region | Specific recognition element |
| U2AF homology motif (UHM) | Interfaces with U2AF1 |
| Polypyrimidine tract | Stretch of 10-20 pyrimidines (U/C) preceding the splice site |
| 3' AG dinucleotide | The absolutely conserved terminal nucleotides |
| Associated Diseases | Als, Ms |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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