gene 1,224 words KG: RBFOX1 2026-03-24
kind:genesection:genesstate:published
Contents

RNA Binding Fox-1 Homolog 1 (RBFOX1)

🧬 Gene Info
Gene SymbolRBFOX1
Full NameRNA Binding Fox-1 Homolog 1 (RBFOX1)
AliasesA2BP1
Chromosome16p13.3 [@zha2023]
Protein TypeGene
FunctionNeuronal Splicing Programs: Controls inclusion/exclusion of alternative exons in hundreds of neuronal transcripts.
Molecular Weight47.6 kDa
Amino Acids90 aa
UniProt IDQ9NWB1
NCBI Gene ID23027
Ensembl IDENSG00000078328
GeneCardsRBFOX1
Human Protein AtlasRBFOX1
Associated DiseasesALS, Alzheimer, Ms, dementia, neurodegeneration
InteractionsANO3
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Cryptic Exon Silencing Restoration
Score: 0.46
Cross-Seeding Prevention Strategy
Score: 0.45
Glycine-Rich Domain Competitive Inhibition
Score: 0.43
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.41
RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.37

Related Analyses (11)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
What determines the specificity of RNA-protein interactions
neurodegeneration · failed
How do dilncRNAs specifically drive molecular crowding and p
neurodegeneration · completed
What determines the specificity of DDR protein recruitment t
neurodegeneration · completed
Do chronic stress granule inhibition strategies impair norma
neurodegeneration · failed

Related Experiments (30)

Myricanol treatment in HFD-induced hyperlipidemic C57BL/6J m
validation · proposed · Score: 0.95
Single-cell RNA-seq analysis of mouse testes with gonadal de
exploratory · proposed · Score: 0.95
Sevoflurane-induced neurotoxicity (SIN) rat model
validation · proposed · Score: 0.95
FLS Stimulation and Transcriptomic Analysis
exploratory · proposed · Score: 0.95
Factor depletion effects on DDR focus formation in vivo
exploratory · proposed · Score: 0.90

See Also (5)

Packard Center for ALS Research
institution · KG edge: associated_with
u2af2
gene · KG edge: associated_with
ANO3 Gene
gene · KG edge: interacts_with
Neurons
entity · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (12 edges)

RBFOX1 associated_with U2AF2
RBFOX1 associated_with Als
RBFOX1 associated_with Ms
RBFOX1 expressed_in neurons
RBFOX1 interacts_with amyloid aggregation
RBFOX1 associated_with neurodegeneration
RBFOX1 associated_with ALS
RBFOX1 associated_with dementia
RBFOX1 associated_with Alzheimer
ANO3 interacts_with RBFOX1