| Gene Symbol | UBXD1 |
| Chromosome | 19p13.3 |
| Protein Family | UBX Domain Family, UBXN Family |
| Function | ER-Associated Degradation (ERAD): UBXD1 recruits ubiquitinated substrates to the p97 ATPase complex for extraction from the ER membrane into the cytosol, where they are degraded by the 26S proteasome[ |
| Primary Expression | human tissues, with high expression in brain (particularly neurons), heart, and liver |
| Subcellular Localization | Endoplasmic Reticulum, Cytoplasm, Nucleus |
| Molecular Weight | 43 kDa |
| Amino Acids | 377 aa |
| Exons | 9 |
| Pathways | autophagy pathway, ubiquitin-proteasome |
| UniProt ID | Q9Y5J7 |
| GeneCards | UBXD1 |
| Human Protein Atlas | UBXD1 |
| Associated Diseases | neurodegeneration |
| Interactions | VCP, UFD1, NPL4 |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |