| Gene Symbol | ATP13A2 |
| Full Name | ATPase Cation Transporting 13A2 |
| Chromosome | 1p36.13 |
| Protein Type | Protein |
| Function | is a member of the P-type ATPase family that functions as a lysosomal cation transporter, primarily pumping manganese and other cations across the lysosomal membrane[@ramirez2006]. |
| Primary Expression | Substantia nigra, Basal ganglia, Cerebral cortex |
| Subcellular Localization | Lysosomes, late endosomes, secretory vesicles |
| Molecular Weight | ~438 kDa |
| Amino Acids | 978 aa |
| Pathways | Autophagy |
| UniProt ID | Q9BYU8 |
| Ensembl ID | ENSG00000159363 |
| GeneCards | ATP13A2 |
| Human Protein Atlas | ATP13A2 |
| Protein Name | Lysosomal Cation Transporter ATP13A2 |
| Associated Diseases | ALS, AMYOTROPHIC LATERAL SCLEROSIS, Aging, Alzheimer |
| Interactions | VPS35, EIF4G1, PARKIN, NLRP3, FA2H, DNAJC6 |
| KG Connections | 381 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |