| Gene Symbol | CHCHD10 |
| Full Name | Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10 |
| Aliases | CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 |
| Chromosome | 22q11.23 |
| Protein Family | CHCH domain-containing protein family |
| Function | Together they stabilize the mitochondrial contact site and cristae organizing system (MICOS), which maintains cristae morphology essential for efficient OXPHOS (Genin et al., 2016). |
| Primary Expression | Motor cortex, Spinal cord, Mitochondria (widespread) |
| Subcellular Localization | Mitochondrial intermembrane space, cristae junctions |
| Molecular Weight | 14 kDa |
| Amino Acids | 182 aa |
| UniProt ID | Q8WYQ3 |
| NCBI Gene ID | 400916 |
| Ensembl ID | ENSG00000250479 |
| OMIM | 615903 |
| GeneCards | CHCHD10 |
| Human Protein Atlas | CHCHD10 |
| Associated Diseases | ALS, AMYOTROPHIC LATERAL SCLEROSIS, AUTOPHAGY, MITOCHONDRIAL DYSFUNCTION, PARKINSON'S DISEASE |
| Interactions | FUS, GBA, LRRK2, PARK7, PINK1, SNCA |
| KG Connections | 127 knowledge graph edges |
| Databases | GeneCardsHPASTRING |