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mechanism 2,091 words KG: synaptic_dysfunction
Contents

Synaptic Dysfunction in 4R-Tauopathies

⚙ Mechanism Info
Namesynaptic_dysfunction
Key Genes/ProteinsC1Q, protein_oligomers
Related Diseasesearly_AD, neurodegeneration
Related Pathwaysneuroinflammation
Linked Hypotheses1 hypotheses

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (21)

Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60
← Prevpg 2/2

Related Analyses (30)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSynaptic pruning by microglia in early AD
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived

Related Experiments (4)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40Tau depletion effects on neuronal development in primary cul
exploratory · proposed · Score: 0.90Microtubule domain analysis in adult axons
exploratory · proposed · Score: 0.80Pre-Symptomatic Tau Detection in MAPT Mutation Carriers
clinical · proposed · Score: 0.40

See Also (3)

CA2 Pyramidal Neurons
cell · KG edge: causesNeurodegeneration
disease · KG edge: contributes_toC3 — Complement Component 3
gene · KG edge: causes

Knowledge Graph (5 edges)

protein_oligomers causes synaptic_dysfunction
synaptic_dysfunction contributes_to neurodegeneration
C1Q causes synaptic_dysfunction
synaptic_dysfunction biomarker_for early_AD
neuroinflammation causes synaptic_dysfunction

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