| Gene Symbol | DLK2 |
| Full Name | Delta-Like Non-Canonical Notch Ligand 2 |
| Chromosome | 6p25.1 |
| Function | is a single-pass transmembrane protein that functions as a non-canonical Notch ligand. |
| Primary Expression | hematopoietic stem and progenitor cells
- Adipose tissue: Regulated during adipogenesis
- Liver and kidney: Moderate expression in parenchymal |
| Amino Acids | 387 aa |
| Exons | 8 |
| Pathways | Notch, Notch signaling |
| UniProt ID | Q9Y5F7 |
| NCBI Gene ID | 203522 |
| Ensembl ID | ENSG00000154640 |
| OMIM | 612651 |
| GeneCards | DLK2 |
| Human Protein Atlas | DLK2 |
| N-terminal extracellular domain | Contains multiple epidermal growth factor-like (EGF) repeats (typically 6-8) that mediate protein-protein interactions |
| Associated Diseases | neurodegeneration |
| Interactions | NOTCH1, GFAP, EGF, NESTIN, SOX2, VIMENTIN |
| KG Connections | 45 knowledge graph edges |
| Databases | GeneCardsHPASTRING |