| Gene Symbol | ADCY2 |
| Full Name | Adenylate cyclase 2 (Membrane-bound adenylyl cyclase) |
| Aliases | Adenylate Cyclase 2 |
| Chromosome | 5p15.2 |
| Protein Type | Enzyme |
| Function | is a membrane-bound enzyme that catalyzes the conversion of ATP to cyclic adenosine monophosphate (cAMP), a crucial second messenger in cellular signaling. |
| Molecular Weight | 125 kDa |
| UniProt ID | [Q08462](https://www.uniprot.org/uniprot/Q08462) |
| Ensembl ID | ENSG00000045081 |
| OMIM | 103070 |
| GeneCards | ADCY2 |
| Human Protein Atlas | ADCY2 |
| Two transmembrane modules | Each with six transmembrane helices |
| Cytoplasmic catalytic domains | C1a and C2a form the dimeric catalytic core |
| Forskolin binding site | On the C2 domain |
| Associated Diseases | Alzheimer's disease (AD |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, C3AR1, CCR5, CNR2, CXCL12 |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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