C3AR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about C3AR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

C3AR1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in, regulates. Associated with Aging, Als, Alzheimer. Connected to 72 entities in the SciDEX knowledge graph.

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graph TD
    C3AR1["C3AR1"]
    Glioblastoma{"Glioblastoma"}
    C3AR1 -->|"activates"| Glioblastoma
    Tumor{"Tumor"}
    C3AR1 -->|"activates"| Tumor
    Dementia{"Dementia"}
    C3AR1 -->|"regulates"| Dementia
    Glioma{"Glioma"}
    C3AR1 -->|"associated with"| Glioma
    BLOOD_CSF_BARRIER(["BLOOD_CSF_BARRIER"])
    C3AR1 -->|"regulates"| BLOOD_CSF_BARRIER
    M2_POLARIZATION["M2_POLARIZATION"]
    C3AR1 -->|"regulates"| M2_POLARIZATION
    MICROGLIAL_RECRUITMENT["MICROGLIAL_RECRUITMENT"]
    C3AR1 -->|"regulates"| MICROGLIAL_RECRUITMENT
    Complement(["Complement"])
    C3AR1 -->|"associated with"| Complement
    GBM["GBM"]
    C3AR1 -->|"expressed in"| GBM
    GENES["GENES"]
    C3AR1 -->|"biomarker for"| GENES
    DNA["DNA"]
    C3AR1 -->|"regulates"| DNA
    RBPJL["RBPJL"]
    C3AR1 -->|"biomarker for"| RBPJL
    C3A["C3A"]
    C3A -->|"activates"| C3AR1
    SB290157["SB290157"]
    SB290157 -->|"inhibits"| C3AR1
    C3["C3"]
    C3 -->|"activates"| C3AR1
    HYPOXIA["HYPOXIA"]
    HYPOXIA -->|"activates"| C3AR1
    GBM -->|"expressed in"| C3AR1
    COMPLEMENT["COMPLEMENT"]
    COMPLEMENT -->|"associated with"| C3AR1
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| C3AR1
    GLIOBLASTOMA["GLIOBLASTOMA"]
    GLIOBLASTOMA -->|"activates"| C3AR1
    AND["AND"]
    AND -->|"expressed in"| C3AR1
    style C3AR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

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