| Gene Symbol | adra2b |
| Full Name | Alpha-2B Adrenergic Receptor |
| Chromosome | 2q24.1 |
| Protein Family | Class A GPCR, α2-adrenergic family |
| Primary Expression | both the central and peripheral nervous systems, where it regulates norepinephrine release, blood pressure, and various autonomic functions |
| Subcellular Localization | Cell membrane |
| Molecular Weight | ~50-60 kDa |
| Amino Acids | 450 aa |
| Pathways | PI3-K, Wnt |
| UniProt ID | P47820 |
| NCBI Gene ID | 151 |
| Ensembl ID | ENSG00000159692 |
| Protein Name | ADRA2B, Alpha-2B Adrenergic Receptor |
| Ligand | Norepinephrine, epinephrine, clonidine |
| Signal Transduction | Gi/o protein, ↓cAMP |
| Associated Diseases | neurodegeneration |
| Interactions | IL13, WNT11, TNFRSF1B, TNFRSF13C, MYO7A, WNT1 |
| KG Connections | 77 knowledge graph edges |
| Databases | GeneCardsHPASTRING |