| Gene Symbol | ANK2PROTEIN |
| Full Name | Ankyrin B |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | the axon initial segment (AIS), nodes of Ranvier, and the endoplasmic reticulum-plasma membrane interface in neurons, wh |
| UniProt ID | Search UniProt |
| GeneCards | ANK2PROTEIN |
| Human Protein Atlas | ANK2PROTEIN |
| Ankyrin Alpha | Related membrane adaptor protein with distinct tissue distribution and protein-binding partners |
| Spectrin | Primary cytoskeletal binding partner of Ankyrin B |
| Na+/K+-ATPase | Major functional cargo of Ankyrin B |
| Nodes of Ranvier | Critical neuronal microdomains dependent on Ankyrin B organization |
| Axon Initial Segment | Primary neuronal compartment requiring Ankyrin B for structural maintenance |
| Amyloid Precursor Protein | Potential Ankyrin B-interacting protein relevant to Alzheimer's disease pathophysiology |
| Associated Diseases | neurodegeneration |
| Interactions | COMPLEMENT, IGF2BP1, PTEN |
| SciDEX Hypotheses | Neuronal-specific domain stabilization |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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