| Gene Symbol | ARHGEF2 |
| Full Name | Rho Guanine Nucleotide Exchange Factor 2 |
| Chromosome | 1q22 |
| Protein Family | Dbl family RhoGEF |
| Function | ARHGEF2 encodes a Rho GEF that activates Rho GTPases, primarily RhoA, but also Rac1 and Cdc42. |
| Molecular Weight | ~220 kDa |
| Amino Acids | 736 aa |
| Exons | 33 |
| UniProt ID | Q9NRY4 |
| NCBI Gene ID | 9199 |
| Ensembl ID | ENSG00000116584 |
| OMIM | 607560 |
| GeneCards | ARHGEF2 |
| Human Protein Atlas | ARHGEF2 |
| Protein Name | Rho Guanine Nucleotide Exchange Factor 2 |
| Associated Diseases | Intellectual disability, Midbrain-hindbrain malformation |
| Interactions | RhoA, Rac1, CaMKK2, SQSTM1, TPM3, NPM1 |
| KG Connections | 38 knowledge graph edges |
| Databases | GeneCardsHPASTRING |