LMNA

Understanding Entity Pages

This page aggregates everything SciDEX knows about LMNA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

LMNA is a gene implicated in neurodegeneration research. Key relationships include: interacts with, therapeutic target, associated with. Associated with AD, ALI, ALS. Connected to 420 entities in the SciDEX knowledge graph.

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graph TD
    LMNA["LMNA"] -->|"Encodes"| Lamin_AC["Lamin_AC"]
    LMNA["LMNA"] -->|"Causes"| DCM["DCM"]
    LMNA["LMNA"] -->|"Interacts With"| Alzheimer["Alzheimer"]
    LMNA["LMNA"] -->|"Interacts With"| Tumor["Tumor"]
    LMNA["LMNA"] -->|"Interacts With"| Als["Als"]
    LMNA["LMNA"] -->|"Interacts With"| Dementia["Dementia"]
    LMNA["LMNA"] -->|"Interacts With"| Cardiovascular["Cardiovascular"]
    LMNA["LMNA"] -->|"Interacts With"| Parkinson["Parkinson"]
    NCSTN["NCSTN"] -->|"Interacts With"| LMNA["LMNA"]
    FAS["FAS"] -->|"Interacts With"| LMNA["LMNA"]
    TNF["TNF"] -->|"Interacts With"| LMNA["LMNA"]
    CAT["CAT"] -->|"Interacts With"| LMNA["LMNA"]
    OPTN["OPTN"] -->|"Interacts With"| LMNA["LMNA"]
    style LMNA fill:#8d4900,color:#e0e0e0
    style Lamin_AC fill:#0d47a1,color:#e0e0e0
    style DCM fill:#b71c1c,color:#e0e0e0
    style Alzheimer fill:#b71c1c,color:#e0e0e0
    style Tumor fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Dementia fill:#b71c1c,color:#e0e0e0
    style Cardiovascular fill:#b71c1c,color:#e0e0e0
    style Parkinson fill:#b71c1c,color:#e0e0e0
    style NCSTN fill:#8d4900,color:#e0e0e0
    style FAS fill:#8d4900,color:#e0e0e0
    style TNF fill:#8d4900,color:#e0e0e0
    style CAT fill:#8d4900,color:#e0e0e0
    style OPTN fill:#8d4900,color:#e0e0e0