protein 1,685 words KG: AURKBPROTEIN
Contents

AURKBPROTEIN Protein

🔬 Protein Info
Gene SymbolAURKBPROTEIN
Chromosome17p13.1
Protein FamilyAurora kinase family
Protein TypeSerine/Threonine Kinase
Functionis a chromosomal passenger protein and serine/threonine kinase that plays critical roles in mitosis, cytokinesis, and regulation of histone modifications.
Primary Expressionpost-mitotic neurons where it performs distinct functions
Subcellular LocalizationCentromere, midbody, nucleus
Molecular Weight~39 kDa
UniProt IDQ96GD4
GeneCardsAURKBPROTEIN
Human Protein AtlasAURKBPROTEIN
Protein NameAURKB (Aurora Kinase B)
GeneAURKB
Protein ClassSerine/Threonine kinase
Brain ExpressionHigh in developing neurons, moderate in adult brain
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsMYC, CALM1, KIF5B, PVALB, SST, RANK
KG Connections88 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph