CALM1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CALM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CALM1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, interacts with, associated with. Associated with Als, Autism, Carcinoma. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    CALM1["<b>CALM1</b>"]
    Ms{"Ms"}
    CALM1 -->|"interacts with"| Ms
    Carcinoma{"Carcinoma"}
    CALM1 -->|"interacts with"| Carcinoma
    CALM1 -->|"associated with"| Ms
    Autism{"Autism"}
    CALM1 -->|"expressed in"| Autism
    Als{"Als"}
    CALM1 -->|"therapeutic target"| Als
    Cardiac{"Cardiac"}
    CALM1 -->|"therapeutic target"| Cardiac
    CALM1 -->|"therapeutic target"| Ms
    HSP90AA1["HSP90AA1"]
    CALM1 -->|"interacts with"| HSP90AA1
    JUN["JUN"]
    CALM1 -->|"interacts with"| JUN
    Akt(["Akt"])
    CALM1 -->|"interacts with"| Akt
    ACTB["ACTB"]
    CALM1 -->|"associated with"| ACTB
    CALM1 -->|"associated with"| JUN
    TP53["TP53"]
    TP53 -->|"interacts with"| CALM1
    SOD1["SOD1"]
    SOD1 -->|"interacts with"| CALM1
    AKT1["AKT1"]
    AKT1 -->|"interacts with"| CALM1
    EGFR["EGFR"]
    EGFR -->|"interacts with"| CALM1
    MAPK1["MAPK1"]
    MAPK1 -->|"associated with"| CALM1
    RHOA["RHOA"]
    RHOA -->|"associated with"| CALM1
    EGFR -->|"associated with"| CALM1
    KCNH2["KCNH2"]
    KCNH2 -->|"therapeutic target"| CALM1
    IDH1["IDH1"]
    IDH1 -->|"therapeutic target"| CALM1
    TP53 -->|"therapeutic target"| CALM1
    SCN5A["SCN5A"]
    SCN5A -->|"therapeutic target"| CALM1
    IL1B["IL1B"]
    IL1B -->|"therapeutic target"| CALM1
    style CALM1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0