ACTB

Understanding Entity Pages

This page aggregates everything SciDEX knows about ACTB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ACTB is a gene implicated in neurodegeneration research. Key relationships include: associated with, interacts with, regulates. Associated with AD, ADH, ALI. Connected to 568 entities in the SciDEX knowledge graph.

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flowchart TD
    ACTB(["ACTB"])
    Autophagy["Autophagy"]
    AUTOPHAGY(["AUTOPHAGY"])
    Als["Als"]
    SQSTM1(["SQSTM1"])
    PPARGC1A(["PPARGC1A"])
    ATG14(["ATG14"])
    LAMP1(["LAMP1"])
    LC3(["LC3"])
    P62(["P62"])
    EGFR(["EGFR"])
    ALS(["ALS"])
    BECN1(["BECN1"])

    ACTB -->|"associated with"| Autophagy
    ACTB -->|"associated with"| AUTOPHAGY
    ACTB -->|"interacts with"| Als
    ACTB -->|"regulates"| SQSTM1
    ACTB -->|"regulates"| PPARGC1A
    ACTB -->|"associated with"| ATG14
    ACTB -->|"activates"| LAMP1
    ACTB -->|"activates"| LC3
    ACTB -->|"regulates"| P62
    ACTB -->|"activates"| P62
    ACTB -->|"associated with"| P62
    ACTB -->|"interacts with"| EGFR
    ACTB -->|"interacts with"| ALS
    BECN1 -->|"associated with"| ACTB
    SQSTM1 -->|"activates"| ACTB

    style ACTB fill:#006494,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0