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protein 1,153 words KG: AUXILINPROTEIN
Contents

Auxilin Protein

🔬 Protein Info
Gene SymbolAUXILIN
AliasesAUXILINPROTEIN
Chromosome1p31.3
FunctionAuxilin is specifically expressed in neurons and neuroendocrine cells where CME is heavily used.
Molecular Weight97 kDa
Amino Acids826 aa
Exons15
GeneCardsAUXILIN
Human Protein AtlasAUXILIN
Associated DiseasesParkinson's disease, Alzheimer's disease, ALS
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (21)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68LRP1-Dependent Tau Uptake Disruption
Score: 0.60Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76APOE Isoform Expression Across Glial Subtypes
Score: 0.74APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72APOE Isoform Conversion Therapy
Score: 0.72Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
pg 1/2Next →

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedProtein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Endosomal-Lysosomal Pathway in Neurodegeneration
mechanism · Pages share 6 hypothesesPPAR Signaling Pathway in Neurodegeneration
mechanism · Pages share 6 hypothesesNeurovascular Unit Dysfunction in Neurodegeneration
mechanism · Pages share 6 hypothesesEndosomal Sorting Defects in Neurodegeneration
mechanism · Pages share 6 hypothesesSenescent Cell Clearance in Neurodegeneration
mechanism · Pages share 6 hypotheses

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