| Gene Symbol | CAML |
| Aliases | Calcium Modulator and Cyclophilin Ligand |
| Protein Type | Gene |
| Function | encodes a group of serine/threonine kinases that play critical roles in neuronal signaling, synaptic plasticity, and cognitive function. |
| Primary Expression | the forebrain, particularly in hippocampal CA1 neurons and cortical pyramidal cells[@lisman2002]
- CAMK2B: Expressed throughout the brain, with hi |
| Subcellular Localization | Endoplasmic reticulum, plasma membrane |
| Molecular Weight | ~64 kDa |
| GeneCards | CAML |
| Human Protein Atlas | CAML |
| Protein Name | CAML (Calcium Modulator and Cyclophilin Ligand) |
| Alternative Names | UNC93B1, TMEM111 |
| Gene | UNC93B1 |
| Transmembrane Domains | 12 transmembrane helices |
| Drug | Target |
| GSK-7974437 | CRAC |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |