| Gene Symbol | CASPASE1 |
| Aliases | CASPASE1PROTEIN |
| Function | Caspase-1 (interleukin-1β-converting enzyme, ICE) is the prototypical inflammatory caspase, playing a central role in innate immunity and inflammatory cell death (pyroptosis) |
| Subcellular Localization | Cytosol, inflammasome complex |
| Molecular Weight | 45 kDa (pro-form), 20/10 kDa (cleaved subunits) |
| UniProt ID | [P29466](https://www.uniprot.org/uniprot/P29466) |
| GeneCards | CASPASE1 |
| Human Protein Atlas | CASPASE1 |
| Associated Diseases | ALS |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |