| Gene Symbol | CHRNA5 |
| Full Name | Cholinergic Receptor Nicotinic Alpha Subunit 5 |
| Aliases | CHRNA5PROTEIN |
| Chromosome | 15q25.1 |
| Protein Family | Cys-loop receptor family; Nicotinic acetylcholine receptor |
| Protein Type | Channel |
| Function | CHRNA5 encodes the alpha-5 subunit of nicotinic receptors. |
| Primary Expression | the central nervous system, particularly in the hippocampus, cortex, and basal ganglia[@albuque |
| Subcellular Localization | Plasma membrane (neuronal ligand-gated ion channel) |
| Molecular Weight | ~53 kDa |
| Pathways | ubiquitin-proteasome |
| UniProt ID | P43680 |
| GeneCards | CHRNA5 |
| Human Protein Atlas | CHRNA5 |
| Protein Name | Nicotinic acetylcholine receptor subunit alpha-5 |
| Associated Diseases | Addiction, Opioid, nicotine_dependence |
| Interactions | DRD2, AND |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |