| Gene Symbol | CYTOCHROMEC |
| Aliases | CYTOCHROMECPROTEIN |
| Function | The discovery that cytochrome c functions as both an electron carrier and an apoptosis initiator has profound implications for understanding neurodegeneration. |
| Subcellular Localization | </b></td><td>Mitochondrial intermembrane space</td></tr> |
| GeneCards | CYTOCHROMEC |
| Human Protein Atlas | CYTOCHROMEC |
| Ferric form (Fe³⁺) | Oxidized state, paramagnetic |
| Ferrous form (Fe²⁺) | Reduced state, diamagnetic |
| Phosphorylation | Tyrosine phosphorylation at residue 97 can inhibit apoptosis by preventing cytochrome c release[@ferrer2023] |
| Acetylation | Lysine acetylation affects its interaction with apoptotic proteins |
| Nitrosylation | S-nitrosylation can modulate its pro-apoptotic activity[@stanimirovic2023] |
| ATP depletion | Reduced oxidative phosphorylation capacity |
| Metabolic stress | Inability to meet neuronal energy demands[@mattson2023] |
| Known Drugs/Compounds | Methylene Blue, ANTHOCYANINS |
| Interactions | UBIQUITIN, ATG7, LC3B, COX4I1, OPTINEURIN, HSP60 |
| KG Connections | 64 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |