| Gene Symbol | DAG1PROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | [@muntoni2008] | Plasma membrane, cell surface [@bakker2016] |- [@tian2010] \! P |
| Molecular Weight | 156 kDa |
| Amino Acids | 895 aa |
| GeneCards | DAG1PROTEIN |
| Human Protein Atlas | DAG1PROTEIN |
| N-terminal domain (NTD) | Ig-like fold involved in binding ECM proteins [2] |
| Mucin-like domain | Heavily O-glycosylated region that mediates interactions with laminin, agrin, and perlecan [3] |
| C-terminal domain | Forms a β-sheet that interacts with β-dystroglycan [4] |
| Extracellular domain | Contains the binding site for α-dystroglycan |
| Transmembrane domain | Single pass through the lipid bilayer |
| Cytoplasmic domain | Binds to dystrophin and utrophin via its C-terminal tail [5] |
| Associated Diseases | AD, Als, fibrosis, LOAD, Muscular Dystrophy |
| Interactions | BCL-2, DYSTROGLYCAN, RNA, TOLL |
| KG Connections | 50 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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