Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DYSTROGLYCAN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | DYSTROGLYCAN |
| Molecular Weight | 156 kDa |
| Amino Acids | 895 aa |
| GeneCards | DYSTROGLYCAN |
| Human Protein Atlas | DYSTROGLYCAN |
| Interactions | BCL-2, DAG1, IGF1R |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
DYSTROGLYCAN(["DYSTROGLYCAN"])
FIBROSIS["FIBROSIS"]
BCL_2(["BCL-2"])
HSPG2("HSPG2")
Differentiation("Differentiation")
INSULIN("INSULIN")
FIBROBLASTS("FIBROBLASTS")
DAG1(["DAG1"])
IGF1R(["IGF1R"])
DYSTROGLYCAN -->|"activates"| FIBROSIS
DYSTROGLYCAN -->|"activates"| BCL_2
DYSTROGLYCAN -->|"activates"| HSPG2
DYSTROGLYCAN -->|"activates"| Differentiation
DYSTROGLYCAN -->|"activates"| INSULIN
DYSTROGLYCAN -->|"activates"| FIBROBLASTS
DAG1 -->|"activates"| DYSTROGLYCAN
IGF1R -->|"activates"| DYSTROGLYCAN
style DYSTROGLYCAN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| FIBROSIS | activates | disease | 0.50 |
| BCL-2 | activates | protein | 0.50 |
| HSPG2 | activates | concept | 0.50 |
| INSULIN | activates | concept | 0.50 |
| FIBROBLASTS | activates | concept | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||