protein 778 words KG: DNAJA1PROTEIN
Contents

DNAJA1/Hsp40 Protein

🔬 Protein Info
Gene SymbolDNAJA1
Full NameDnaJ Heat Shock Protein Family (Hsp40) Member A1
Chromosome9p13.3
Protein FamilyDnaJ/Hsp40 family
Protein TypeChaperone
Functionis an important component in the neurobiology of neurodegenerative diseases.
UniProt ID[P31689](https://www.uniprot.org/uniprot/P31689)
NCBI Gene ID1652
Ensembl IDENSG00000116001
OMIM601067
GeneCardsDNAJA1
Human Protein AtlasDNAJA1
J Domain (~70 amino acids)The defining feature of DnaJ proteins, stimulates Hsp70 ATPase activity
Glycine/Phenylalanine (G/F)-Rich RegionFlexible linker with low complexity
C-terminal Substrate-Binding DomainBinds client proteins for delivery to Hsp70
Associated Diseasesneurodegeneration
InteractionsABCB1, ALZHEIMER, ALZHEIMER'S DISEASE, ATP1B1, ATP1B3, DNAJB1
KG Connections63 knowledge graph edges
DatabasesGeneCardsHPASTRING

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