protein 750 words KG: FASLGPROTEIN
Contents

FASLG Protein - Fas Ligand

🔬 Protein Info
Gene SymbolFASLG
Full NameFASLG - Fas Ligand
AliasesFASLGPROTEIN
Chromosome1q24.3
Protein TypeGene
Functionis a gene encoding the Fas ligand (FasL/CD95L), a Type II transmembrane protein belonging to the tumor necrosis factor (TNF) superfamily.
Primary Expressionvarious tissues with notable patterns relevant to neurodegeneration: [@yang2006]
Molecular Weight26 kDa
PathwaysNF-κB
UniProt IDP48023
NCBI Gene ID3564
GeneCardsFASLG
Human Protein AtlasFASLG
Associated Diseasesneurodegeneration
KG Connections1 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Related Hypotheses (15)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
APOE Isoform Conversion Therapy
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

See Also (15)

A Phase 2 Double-Blind, Randomized, Placebo-Controlled
clinical · Pages share 7 hypotheses
BEACoN Study - Biomarker Exploration in Aging, Cognitio
clinical · Pages share 7 hypotheses
A Phase IIB, Randomized, Double-Blind, Placebo-Controll
clinical · Pages share 7 hypotheses
Beta-Propeller Protein-Associated Neurodegeneration (BP
disease · Pages share 6 hypotheses
Neuroimaging Biomarkers for Neurodegeneration
biomarker · Pages share 6 hypotheses

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