protein 2,692 words KG: IL1APROTEIN 2026-03-28
kind:proteinsection:proteinstopic:alzheimerstopic:parkinsonstopic:neuroinflammation
Contents

IL-1α Protein

🔬 Protein Info
Gene SymbolIL
Full Name1α Protein — Interleukin-1 Alpha
AliasesIL1APROTEIN
FunctionInterleukin-1 beta (IL-1β) is a potent pro-inflammatory cytokine that plays a central role in the innate immune response and neuroinflammation.
Subcellular Localization</strong></td><td>Cytoplasm, membrane-bound, secreted</td></tr>
GeneCardsIL
Human Protein AtlasIL
Associated DiseasesCRC
KG Connections1 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (23)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.55
Epigenetic Memory Erasure via TET2 Activation
Score: 0.52
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Astrocyte-Microglia Communication Rebalancing via Cytokine M
Score: 0.49

Related Analyses (10)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (1)

Proposed experiment from debate on Microglia activate astroc
falsification · proposed · Score: 0.40

See Also (15)

Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 8 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 8 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 8 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 8 hypotheses
Vagus Nerve Pathway in Neurodegeneration
mechanism · Pages share 8 hypotheses