protein 608 words KG: IL6STPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

IL6 Signal Transducer (gp130/IL6ST) Protein

🔬 Protein Info
Gene SymbolIL6STPROTEIN
Chromosome5q11.2.
Functionis a critical mediator of neuroinflammation and neurotrophic signaling in the central nervous system.
Molecular Weight130 kDa
Amino Acids917 aa
GeneCardsIL6STPROTEIN
Human Protein AtlasIL6STPROTEIN
YXXQ motifsMultiple
SHP2 bindingY759
AgentStatus
IL-6Experimental
CNTFClinical trials
Hyper-IL-6Preclinical
TocilizumabApproved (RA)
SarilumabApproved
Associated Diseasesneurodegeneration
InteractionsJAK2, MYC, GATA1, NR3C1, CREBBP, LRP1
KG Connections64 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph