GATA1

Understanding Entity Pages

This page aggregates everything SciDEX knows about GATA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GATA1 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, therapeutic target, activates. Associated with Cancer, Carcinoma, Tumor. Connected to 18 entities in the SciDEX knowledge graph.

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graph TD
    GATA1["<b>GATA1</b>"]
    AGGF1["AGGF1"]
    GATA1 -->|"upregulates"| AGGF1
    Carcinoma{"Carcinoma"}
    GATA1 -->|"interacts with"| Carcinoma
    Cancer{"Cancer"}
    GATA1 -->|"interacts with"| Cancer
    Tumor{"Tumor"}
    GATA1 -->|"interacts with"| Tumor
    HSP70["HSP70"]
    GATA1 -->|"activates"| HSP70
    APOPTOSIS["APOPTOSIS"]
    GATA1 -->|"therapeutic target"| APOPTOSIS
    Apoptosis(["Apoptosis"])
    GATA1 -->|"therapeutic target"| Apoptosis
    MYC["MYC"]
    GATA1 -->|"interacts with"| MYC
    CANCER["CANCER"]
    GATA1 -->|"interacts with"| CANCER
    GATA1 -->|"interacts with"| APOPTOSIS
    CREBBP["CREBBP"]
    GATA1 -->|"interacts with"| CREBBP
    IL6ST["IL6ST"]
    GATA1 -->|"interacts with"| IL6ST
    SNCA["SNCA"]
    SNCA -->|"contributes to"| GATA1
    P53["P53"]
    P53 -->|"activates"| GATA1
    LRP1["LRP1"]
    LRP1 -->|"interacts with"| GATA1
    NR3C1["NR3C1"]
    NR3C1 -->|"interacts with"| GATA1
    style GATA1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0