protein 1,006 words KG: LRP6PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

LRP6 Protein

🔬 Protein Info
Gene SymbolLRP6
AliasesLRP6PROTEIN
Chromosome12p13.2
Protein TypeReceptor
FunctionWnt ligand binds to LRP6 extracellular domain
Subcellular LocalizationCell membrane
Molecular Weight180 kDa
Pathwayssignaling: **Canonical Pathway Activation:**, Wnt, Wnt signaling
UniProt IDO75151
NCBI Gene ID4040
Ensembl IDENSG00000170054
GeneCardsLRP6
Human Protein AtlasLRP6
LDLR repeats 1-324-600 aa
LDLR repeats 4-6600-900 aa
Associated DiseasesALS
InteractionsLRRK2, WNT3A, APP, AKT, ALZHEIMER'S DISEASE, ALZHEIMER
KG Connections104 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph