| Gene Symbol | NLGN3 |
| Full Name | Neuroligin 3 |
| Chromosome | Xq13.1 |
| Protein Family | Neuroligin family |
| Function | encodes a postsynaptic cell adhesion molecule that is essential for the formation, function, and plasticity of synapses throughout the mammalian brain. |
| Primary Expression | neurons throughout the brain, with particularly high levels in the cerebral cortex, hippocampus, and basal ganglia |
| Subcellular Localization | Postsynaptic membrane, dendritic shafts and spines |
| Molecular Weight | ~161 kDa (glycosylated) |
| Amino Acids | 461 aa |
| Exons | 19 |
| Pathways | Mtor, Neuroprotection, PI3K-mTOR, PI3K-mTOR pathway |
| UniProt ID | Q9NZU4 |
| NCBI Gene ID | 54413 |
| Ensembl ID | ENSG00000174373 |
| OMIM | 300336 |
| GeneCards | NLGN3 |
| Human Protein Atlas | NLGN3 |
| Associated Diseases | ALS, high-grade gliomas |
| Interactions | ADAM10, Rb, BRAIN INJURY, S6K1, AND, NEURON |
| KG Connections | 57 knowledge graph edges |
| Databases | GeneCardsHPASTRING |