| Gene Symbol | PLK4 |
| Full Name | Polo-Like Kinase 4 |
| Aliases | PLK4PROTEIN |
| Chromosome | 4q28.1 |
| Protein Type | Kinase |
| Function | is a serine/threonine protein kinase that serves as the master regulator of centriole duplication, playing a critical role in microtubule organization, ciliogenesis, and cell cycle progression. |
| Primary Expression | the central nervous system: |
| Subcellular Localization | </strong></td><td>Centrosome, nucleus</td></tr> |
| Molecular Weight | 97 kDa |
| Ensembl ID | ENSG00000142792 |
| GeneCards | PLK4 |
| Human Protein Atlas | PLK4 |
| Associated Diseases | Alzheimer, Parkinson |
| Interactions | FCGRT, KAT2A |
| KG Connections | 32 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |