| Gene Symbol | RAPTOR |
| Full Name | Regulatory Associated Protein of mTORC1 |
| Aliases | Raptor protein |
| Chromosome | 17q1.32 |
| Function | RAPTOR (Regulatory-Associated Protein of mTOR) is an essential component of mTOR Complex 1 (mTORC1), serving as a scaffolding protein that recruits substrates to the mTOR kinase. |
| Primary Expression | the nervous system: - High expression: Cerebral cortex, hippocampus, basal forebrain - Mo |
| Molecular Weight | 149 kDa |
| Pathways | mtor, mTOR, PI3K, AMPK |
| UniProt ID | Q8N122 |
| Ensembl ID | ENSG00000141551 |
| GeneCards | RAPTOR |
| Human Protein Atlas | RAPTOR |
| HEAT repeats | Mediate protein-protein interactions |
| WD40 repeat domain (C-terminal) | Forms β-propeller for substrate recognition |
| TOS-binding site | Recognizes TOS (TOR signaling) motif on substrates |
| Associated Diseases | neurodegeneration |
| Interactions | ACETYL-COA, ACLY, ALPHA-SYNUCLEIN, AMPK, AND, ATG5 |
| KG Connections | 109 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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