protein 602 words KG: SMAD6PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

SMAD Family Member 6

🔬 Protein Info
Gene SymbolSMAD6PROTEIN
Chromosome15q22.33
Protein FamilySMAD family (inhibitory)
Functionis a SMAD family (inhibitory) member.
Subcellular LocalizationCytoplasm, nucleus
Molecular Weight49 kDa
UniProt IDO43541
GeneCardsSMAD6PROTEIN
Human Protein AtlasSMAD6PROTEIN
Protein NameSMAD Family Member 6
GeneSMAD6
PDB IDs1NX7, 1U2U, 3WOT
Associated DiseasesAls, Alzheimer, Autoimmune, Cancer, Carcinoma, Diabetes
InteractionsTET2
KG Connections43 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (10)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40
CRISPR Gene Correction Approaches for CBS/PSP
clinical · proposed · Score: 0.40
Epigenetic Regulation Dysfunction in Alzheimer's and Parkins
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in