| Gene Symbol | TDP1PROTEIN |
| Protein Type | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | ** | Nucleus, Cytoplasm | |
| Molecular Weight | 68 kDa |
| GeneCards | TDP1PROTEIN |
| Human Protein Atlas | TDP1PROTEIN |
| Domain architecture | TDP1 Family domain organization |
| Key motifs | DNA-binding domains, catalytic residues |
| Post-translational modifications | Phosphorylation, ubiquitination, SUMOylation |
| DNA repair | Essential for maintaining genomic integrity |
| Cell survival | Coordinates DNA damage response with cell survival |
| Neuronal function | Required for long-term neuronal survival |
| Genome stability | Prevents accumulation of mutations |
| Neurodegeneration | Impaired DNA repair leads to neuronal dysfunction |
| Associated Diseases | neurodegeneration |
| Interactions | App, CANCER, DNA, FEN1, HIF1A, NEURODEGENERATIVE DISEASES |
| KG Connections | 42 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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