| Gene Symbol | TNFAIP3 |
| Full Name | TNF alpha induced protein 3 (A20) |
| Aliases | A20, TNFIP3, OTU domain containing 7 |
| Chromosome | 6q23.3 |
| Protein Family | A20 family, OTU domain deubiquitinases |
| Function | The NF-κB pathway controls the expression of inflammatory cytokines, chemokines, and survival genes. |
| Primary Expression | microglia, astrocytes, and neurons, where it controls neur |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | ~90 kDa (790 amino acids) |
| Amino Acids | 790 aa |
| Exons | 9 |
| Pathways | NF-κB, NF-κB signaling |
| UniProt ID | [P21579](https://www.uniprot.org/uniprot/P21579) |
| Ensembl ID | ENSG00000118503 |
| OMIM | 191163 |
| GeneCards | TNFAIP3 |
| Human Protein Atlas | TNFAIP3 |
| Associated Diseases | Als, Ms |
| Interactions | NEK7, NLRP3, CGAS, STING, UBIQUITIN, TNF |
| KG Connections | 88 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |