protein 1,297 words KG: PTPRCPROTEIN 2026-03-27
kind:proteinsection:proteinsstate:publishedtopic:alzheimerstopic:parkinsonstopic:neuroinflammation
Contents

PTPRC Protein - Protein Tyrosine Phosphatase Receptor Type C

🔬 Protein Info
Gene SymbolPTPRC
AliasesPTPRCPROTEIN
FunctionCD45 is a large transmembrane protein characterized by an heavily glycosylated extracellular domain, a single transmembrane helix, and an intracellular tyrosine phosphatase domain.
Subcellular Localization</strong></td><td>Cell membrane (type I transmembrane)</td></tr>
Molecular Weight220 kDa
GeneCardsPTPRC
Human Protein AtlasPTPRC
Associated DiseasesAlzheimer's disease, Parkinson's disease
Known Drugs/CompoundsTRETINOIN (ATRA)
InteractionsALZHEIMER, AMYLOID, IL-6, NF-ΚB, PI3K, RNA
KG Connections8 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph