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mechanism 2,592 words KG: pyroptosis 2026-03-23
kind:mechanismsection:state:published
Contents

Pyroptosis

⚙ Mechanism Info
Namepyroptosis
SummaryInflammatory programmed cell death mediated by gasdermin pore-forming , with key roles in neurodegeneration
Key Genes/ProteinsGSDME, NLRP3, GSDMD, ULK1, IL-1β
Related PathwaysNLRP3 inflammasome, unfolded protein response

Knowledge Graph

Knowledge Graph (12 edges)

pyroptosis active_in microglia
pyroptosis active_in spinal cord
pyroptosis crosstalk_with unfolded protein response
pyroptosis active_in neurons
pyroptosis active_in dopaminergic neurons
pyroptosis active_in macrophages
pyroptosis active_in astrocytes
pyroptosis active_in white matter
pyroptosis active_in endothelial cells
pyroptosis active_in hippocampus
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