gene 504 words KG: SENP2
Contents

SENP2 — SUMO Specific Peptidase 2

🧬 Gene Info
Gene SymbolSENP2
Full NameSUMO Specific Peptidase 2
AliasesPage for SENP2 Protein
Protein TypeProtease
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight68 kDa
Amino Acids589 aa
PathwaysWnt
UniProt ID[Q9Y2W1](https://www.uniprot.org/uniprot/Q9Y2W1)
GeneCardsSENP2
Human Protein AtlasSENP2
SUMO-2/3 processingPrefers SUMO-2 and SUMO-3 precursors
Chain editingEfficiently processes SUMO-2/3 chains
Spatial restrictionFunctions at the nuclear envelope
RANGAP1 processingCritically processes RANGAP1 for RanGAP1 SUMOylation
Associated Diseasesneurodegeneration
InteractionsATF3
KG Connections7 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Targeting AQP4 Sumoylation to Enhance Glymphatic Clearance a
Score: 0.49

Knowledge Graph (7 edges)

TP53 expressed_in SENP2
UBIQUITIN expressed_in SENP2
ATF3 activates SENP2
SENP2 expressed_in UBE2I
P53 expressed_in SENP2
SENP2 expressed_in Als
SENP2 expressed_in Ms

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