| Gene Symbol | ent-gene-9f063e98 |
| Armadillo repeats | Protein-protein interactions |
| Ankyrin repeats | Protein-protein interactions |
| Leucine-rich repeat (LRR) | Substrate recognition |
| ROC GTPase domain | GTP binding/hydrolysis |
| COR domain | Interdomain regulation |
| Kinase domain | Catalytic (ATP binding) |
| WD40 repeats | Protein interactions |
| Compound | Company |
| BIIB122 (DNL151) | Biogen/Denali |
| DNL201 | Denali |
| MLK-1468 | Merck |
| DNL151 | Denali |
| Approach | Target |
| LRRK2 ASOs | LRRK2 mRNA |
| Allele-selective ASOs | Mutant allele |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |