Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 5,593 pages matching "gene"

GenesKG

index · 271 words · 198 hyp29 ana28 exp

💊 AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery AlternativesKG

therapeutic · 15,567 words · 67 hyp24 ana25 exp

⚙️ Parthanatos in NeurodegenerationKG

mechanism · 6,619 words · 278 hyp52 ana55 exp

🏥 Corticobasal Degeneration (CBD)KG

disease · 5,823 words · 18 hyp5 ana9 exp

🧬 NPM1 GeneKG

gene · 5,653 words · 22 hyp11 ana6 exp

🧬 GRIA3 GeneKG

gene · 5,408 words · 3 hyp3 ana1 exp

💊 coq10-neurodegenerationKG

therapeutic · 5,142 words · 286 hyp50 ana57 exp

⚙️ GSK-3β in NeurodegenerationKG

mechanism · 5,020 words · 283 hyp52 ana57 exp

🧬 CNTN5 — Contactin 5KG

gene · 4,980 words · 1 hyp1 ana1 exp

🧬 CLCN10 — Chloride Voltage-Gated Channel 10KG

gene · 4,939 words · 5 hyp5 ana12 exp

⚙️ Circadian Rhythm in NeurodegenerationKG

mechanism · 4,939 words · 286 hyp59 ana71 exp

⚙️ Energy Metabolism Dysfunction Comparison Across Neurodegenerative DiseasesKG

mechanism · 4,869 words · 38 hyp41 ana5 exp

⚙️ Blood-Brain Barrier Dysfunction in NeurodegenerationKG

mechanism · 4,726 words · 331 hyp66 ana62 exp

🧬 ncam2KG

gene · 4,719 words · 2 hyp2 ana1 exp

⚙️ Neurotrophin Signaling Pathways in NeurodegenerationKG

mechanism · 4,695 words · 290 hyp57 ana57 exp

🧬 APOC4 — Apolipoprotein C-IVKG

gene · 4,687 words · 34 hyp2 ana

⚙️ Wnt Non-Canonical Signaling Pathways in NeurodegenerationKG

mechanism · 4,664 words · 293 hyp56 ana57 exp

⚙️ Mitophagy Pathway in NeurodegenerationKG

mechanism · 4,637 words · 301 hyp61 ana65 exp

⚙️ TREM2 Microglial Signaling Pathway in NeurodegenerationKG

mechanism · 4,613 words · 329 hyp74 ana95 exp

🧬 CNTN6 — Contactin 6KG

gene · 4,611 words · 5 hyp2 ana1 exp

⚙️ Axonal Transport Dysfunction Comparison Across Neurodegenerative DiseasesKG

mechanism · 4,604 words · 45 hyp47 ana11 exp

💊 omega-3-fatty-acids-neurodegenerationKG

therapeutic · 4,551 words · 294 hyp52 ana83 exp

⚙️ AI and Machine Learning in NeurodegenerationKG

mechanism · 4,541 words · 289 hyp57 ana58 exp

⚙️ Vitamin D Signaling Pathway in NeurodegenerationKG

mechanism · 4,520 words · 294 hyp57 ana57 exp

🧬 CNTN4 — Contactin 4KG

gene · 4,497 words · 1 hyp2 ana6 exp

⚙️ VEGF/Angiogenesis Pathway in NeurodegenerationKG

mechanism · 4,480 words · 287 hyp53 ana60 exp

💊 Coenzyme Q10 for NeurodegenerationKG

therapeutic · 4,452 words · 284 hyp50 ana58 exp

📊 CSF Neurofilament Light Chain (NfL) in NeurodegenerationKG

biomarker · 4,443 words · 278 hyp41 ana162 exp

💊 deferiprone-neurodegenerationKG

therapeutic · 4,392 words · 285 hyp50 ana58 exp

⚙️ Epigenetic Dysregulation in NeurodegenerationKG

mechanism · 4,376 words · 320 hyp62 ana79 exp

⚙️ Mitochondrial Dysfunction in NeurodegenerationKG

mechanism · 4,363 words · 296 hyp59 ana62 exp

⚙️ Epigenetic Dysregulation Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 4,361 words · 54 hyp46 ana46 exp

⚙️ Epigenetic Alterations in Alzheimer's DiseaseKG

mechanism · 4,331 words · 155 hyp71 ana77 exp

⚙️ Pre-symptomatic Conversion Windows in ALS Genetic Risk CarriersKG

mechanism · 4,322 words · 29 hyp51 ana27 exp

⚙️ Copper Dyshomeostasis in NeurodegenerationKG

mechanism · 4,255 words · 281 hyp52 ana54 exp

🧬 CNTN3 — Contactin 3KG

gene · 4,253 words · 5 hyp2 ana1 exp

🧬 ZDHHC13 — Zinc Finger DHHC-Type Containing 13KG

gene · 4,215 words · 2 hyp2 ana5 exp

🧪 FEEMSA Study: Laryngopharyngeal Function in Neurodegenerative Diseases (NCT04706234)KG

clinical · 4,197 words · 10 hyp14 ana3 exp

⚙️ Splice-Modulating Therapies for NeurodegenerationKG

mechanism · 4,197 words · 300 hyp58 ana69 exp

⚙️ Traumatic Brain Injury and Neurodegeneration PathwayKG

mechanism · 4,171 words · 300 hyp66 ana63 exp

⚙️ CREB Signaling in NeurodegenerationKG

mechanism · 4,156 words · 298 hyp61 ana57 exp

⚙️ Excitotoxicity in NeurodegenerationKG

mechanism · 4,129 words · 289 hyp55 ana55 exp

💊 vitamin-d-therapy-neurodegenerationKG

therapeutic · 4,119 words · 296 hyp54 ana61 exp

📊 Cerebrospinal Fluid (CSF) Biomarkers OverviewKG

biomarker · 4,101 words · 31 hyp31 ana22 exp

💊 Neuroprotection Strategies in NeurodegenerationKG

therapeutic · 4,093 words · 317 hyp57 ana71 exp

🧬 MACF1 — Microtubule-actin crosslinking factor 1KG

gene · 4,087 words · 6 hyp4 ana20 exp

⚙️ Gene-Mechanism-Therapy Causal ChainsKG

mechanism · 4,075 words · 104 hyp52 ana21 exp

🧬 KARS1KG

gene · 4,073 words · 9 hyp4 ana5 exp

🧬 RPL30 — Ribosomal Protein L30 in NeurodegenerationKG

gene · 4,066 words · 10 hyp6 ana

⚙️ Protein Aggregation Comparison in NeurodegenerationKG

mechanism · 4,048 words · 294 hyp53 ana68 exp